Career Opportunities

Tufts University Medical Center

Boston, MA

Postdoc Positions

Postdoc positions available to work on one of the following:

1) Regulation of eye lens differentiation,
2) Relationships between protein quality control, aging, disease, dietary glycemia
3) Changes in Ubiquitin conjugate dynamics in response to stress.

Projects are mature and much data is already available. Candidate should have PhD in Biochemistry or related discipline. Candidates with good biochemical, histology skills and experience analyzing large data sets as well as systems approaches are most desired. Candidates should have at least 2 English language first authored papers.

Tufts Medical Center is a highly collaborative and productive environment in downtown Boston, within ~20 minutes from Harvard, MIT, Boston Univ.

Recent papers include:

-Chaffee, B.R… Taylor, A. Nuclear Removal during Terminal Lens Fiber Cell Differentiation Requires CDK1 Activity: Appropriating Mitosis-Related Nuclear Disassembly. Development. (2014) 141:3388-3398. PMID: 25139855.
-Liu, K… Taylor, A. Altering a ubiquitin pathway is associated with perturbed calcium homeostasis, hyperactivation of calpain, and dysregulated differentiation. Proc. Nat. Acad. Sci. 2015 Jan 12 pii: 201404059.
-Lyu, L… Taylor, A. A. FASEB J Unfolded protein response- associated stabilization of p27(Cdkn1b) stabilization interferes with lens fiber denucleation leading to cataract (2016) FASEB J. 2015 Nov 20. pii: fj.15-278036.
-Rowan S… Taylor A. A gut-retina axis and low glycemia arrest of age-related macular degeneration. Proc. Nat. Acad. Sci. in press

Please send CV, a list of grades received in graduate science courses and a mandatory 2 page research proposal of how they would further the objectives of our group, as indicated above, to:

Allen Taylor
Director of the LNVR@HNRCA,
Professor of Nutrition, Biochemistry, and Ophthalmology
Tufts University
711 Washington St
Boston, MA 02111

Email: Allen.Taylor@tufts.edu
2017-05-02 (AdID:16)

University of Houston
Biomedical Engineering
Houston, TX

Postdoctoral Fellow

A postdoctoral position in molecular and gene therapy of retinal diseases is available immediately in the laboratory of Dr. Muna Naash. This position is funded through the National Institute of Health (NIH/NEI). We have several ongoing projects investigating the mechanism of photoreceptor cell death and the application of gene therapy in mice expressing mutant forms of photoreceptor-specific genes that cause retinal diseases in humans. Our laboratory uses approaches that span the structural, electrophysiological, biochemical and molecular levels in studying the visual system. Techniques include basic molecular biology, electrophysiology, light and electron microscopy, protein chemistry, cloning and transgene construction, promoter bashing, yeast one and two hybrid system, and gene therapy.

Requirements:
Ph.D. in Biomedical Science, Biochemistry, Cell and Molecular Biology or related fields with 0-2 years of experience.
Prior experience and knowledge in eye research is preferred.

Interested applicants should submit cover letter and CV to:

Muna I. Naash, PhD
John S. Dunn Professor of Biomedical Engineering
Department of Biomedical Engineering
University of Houston
3517 Cullen Blvd. Room 2011
Houston, TX 77204‐5060
BME Number: 713-743-1651

Email: mnaash@central.uh.edu
2017-04-12 (AdID:15)

Boston Children’s Hospital/Harvard Medical School
Department of Ophthalmology
Boston, MA

Postdoctoral Research Fellow

We seek a talented and motivated candidate to join us as research fellow at Boston Children’s Hospital/Harvard Medical School Department of Ophthalmology in the field of retinal angiogenesis and retinal degeneration studies. The expected start time is summer/fall 2017. This position involves using both genetic and pharmacologic approaches in animal models to study the mechanisms and identify potential therapeutics for pathological angiogenesis in vascular eye diseases, as well as for retinal neuronal degeneration in age-related macular degeneration. This includes (but is not limited to) a specific focus on the investigation of nuclear receptors in vascular and neuronal degeneration in eye diseases, as well as molecular basis underlying blood-retinal barrier control.

Detailed information of the lab can be found at:

http://www.childrenshospital.org/researchers/jing-chen
https://connects.catalyst.harvard.edu/Profiles/display/Person/63020

Requirement:

• M.D. or Ph.D. in biomedical science or related fields with 0-2 years of experience.
• Experience and knowledge in eye research preferred but not required.

Interested candidate please send cover letter and CV to:

Jing Chen, PhD, Assistant Professor of Ophthalmology

Email: jing.chen@childrens.harvard.edu
Website: http://www.childrenshospital.org/researchers/jing-chen
Website: https://connects.catalyst.harvard.edu/Profiles/display/Person/63020
2017-04-11 (AdID:14)




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